Niacinamide regulates the production of facial sebum, accelerates the skin's renewal process by stimulating the formation of collagen and elastin. Normalizes dry skin functions, makes pores appear less visible and brightens skin complexion. Also known as vitamin B3 and vitamin PP. The filler can be used separately or before applying day or night face cream. It can be used in combination with the products of the REFAN ANTI-STRESS Series. For an optimal result, it is recommended to apply the filler before applying the cream.